
Recreate 10 caps
| 90 Capsules | | | Supplement Facts | | Serving Size 1 Capsule | | Servings Per Container 10 | | | Amount Per Serving | % Daily Value* | | | Recreate Blend | 700mg* | | | WillPower (Pure Caralluma Fimbriata), SCModular (Engineered Extract From Coffea Arabica L), ThyriodFast (Engineered Extract From Olea Europaea), Caffeine, Forslean, Cir20x (2-(4-(Beta-D-Gluco-Pyranosyloxy)phenyl)-5-Hydroxy-6, 7-Dimethoxy-4H-1-Benzopyran-4-One Engineered Extract From Microtea Debilis) |
| | * Daily Value not established Other Ingredients: Getatin, Cellulose |
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| Strong Fat Loss!* Looking For A Thermogenic But Don’t Want A Bunch Of Different Stimulants? 
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Directions For USPlabs Recreate: Take 2 capsules 30 minutes before breakfast or morning workout and 1 additional capsule in the afternoon (6-8 hours later) or before an afternoon workout. Do not exceed 4 capsules per day.
While stim-based thermogenics can be very effective, not everyone who wants the benefits of a thermogenic wants a lot of stims…
Some people are just very sensitive, some can’t take them after a certain time of day and some simply just don’t want them.
Until now, low or non-stim burners simply didn’t do the trick…
Fortunately, USPlabs has formulated Recreate – the thermogenic for those who are looking to get cut without having to use a bunch of different stimulants.
Here’s an ingredient breakdown:
Forskolin (Forslean)
An adenlyate cyclase activator, which in turn increases intracellular levels of cAMP (cyclic adenosine monophosphate), which eventually works to stimulate lipolysis in adipose cells.
Beta 2-adrenergic agonists such as ephedrine and clenbuterol actually work by increasing cAMP as well.
Unfortunately, because they work at a receptor, their effectiveness can decrease with continued use as the body down-regulates the number of receptors available.
Forskolin bypasses the receptor and directly activates adenylate cyclase, potentially obviating the need for “cycling” on and off of the product every few weeks.
Another potential benefit is that accumulation of cAMP in skeletal muscle may provide an anti-catabolic/anabolic effect as well (1-5).
A 12 week study, which evaluated body composition, found that when they gave forskolin (i.e., 25 mg twice daily by mouth) to a group of 15 non-active, sedentary, overweight/obese men (without having them change their normal habits), they were able to reduce body fat percentage by a statistically significant (p ≤ 0.05) 4.14 ± 4.47%, versus the placebo group which reduced body fat percentage by 0.96 ± 1.66%.
In addition, they were able to lose a statistically significant amount 4.52 ± 5.74 kg (i.e., approximately 9.9 lb) of fat mass in the forskolin group (placebo lost 0.51 ± 1.91 kg).
While not statistically significant, a trend (p = 0.097) was noted for lean body mass gained in the forskolin group, when compared to baseline; the subjects in the forskolin group gained approximately 8.2 lb of lean body mass (3.71 ± 4.07 kg), while the placebo group gained 1.57 ± 2.56 kg (6).
It also slightly increased free testosterone in these men, but this would not likely occur in women.
Also, while others may cite this study, it was performed using Forslean and only Forslean. While others may claim their product can produce these results, only Forslean was actually used in the study, not theirs.
Other studies have found similar results, while some have found an apparent lack of effects in different populations (e.g., women) (19-22). Still, overall, the use of forskolin for the altering of body composition seems to be effective.
Caffeine
If there were one potential downfall of forskolin, it would be that the body still has a few mechanisms to reduce cAMP levels, either via modulation of adenylate cyclase activity or degradation of cAMP itself.
Caffeine has the potential to work against such mechanisms to increase the effects of forskolin by inhibiting the negative modulation of adenylate cyclase via adenosine antagonism, which is most probable, or potentially (less likely) it’s phosphodiesterase inhibiting effects (7).
Caffeine is a well known stimulant, thermogenic agent and stimulator of fat oxidation in humans.
No fat loss formula would be complete without it (7-10) & the reason caffeine is included is due to this facts and the synergistic effects noted above.
Recreate utilizes just enough caffeine to do the trick, but not the absurd amounts found in many thermogenics today.
Olea europaea
An extract (performed in a very particular way) of olive leaf, was shown to possess potent thyroid stimulatory properties when it increased T3 levels by nearly 150% as compared to the control group in a study using animal models weighing 125-150 g each, using the highest dose group (i.e., a dose of 500 micrograms) (11).
Here is the best part:
Unlike many plant extracts which only have an effect in animal models when the dose employed is the equivalent to a human consuming their entire bodyweight of the substance per day, this actually worked in animal models at a very low dose.
Additionally, the thyroid stimulating effects with this plant in animal model were dose-dependent.
Coffea Arabica L.
Again, a very precise extract of this substance has been shown to inhibit the enzyme 11-B-hydroxysteroid dehydrogenase type 1, both selectively and very potently in vitro (12).
In addition, it was shown to do so in animal muscle and adipose cells, in vitro.
Why is this good?
11beta-HSD1 is an enzyme responsible for converting the very weak glucocorticoid, cortisone, into the much more powerful, cortisol.
We all know that excess cortisol can hamper your progress in the gym, and with the stress of living in our modern world, it’s certain that few people don’t have elevated cortisol levels.
Unfortunately, this particular enzyme works against what we all as athletes and bodybuilders would like and works to increase cortisol levels.
In addition, another sad bit of news is that activity of this enzyme only seems to increase as we get older (13).
By inhibiting 11beta-HSD1, it is thought that it could be used to potentially reduce body fat and improve insulin sensitivity.
Additionally, a beneficial effect upon muscle mass would be expected (14).
Caralluma fimbriata
A very specific extract of this plant was shown to reduce waist size by almost one and a quarter inches in only 8 weeks, while decreasing appetite by approximately 20% as compared to placebo (7) in a study using 23 human male and 39 female subjects (25 subjects completed the study in the active and placebo groups), which were overweight (i.e., BMI > 25 kg/m2).
In addition, those taking the active ingredient (500 mg twice daily of a specific extract) reduced consumption of sweets, refined sugars, cholesterol and saturated fats by the conclusion of the study as compared to placebo.
At the same time, consumption of fruits, vegetables and fish didn’t change.
In other words, it nearly “made” them follow a healthy diet and make better food choices, while also causing them to eat less.
The group taking the caralluma lost 1.5 kg (approximately 3.3 lb) of fat mass as well, over the course of the study.
It has been used for centuries by tribal populations that wished to suppress their appetite.
It also has a well established safety record and had shown no serious adverse effects.
As far as how it works, it is thought that steroidal glycosides present in the plant may increase ATP in the hypothalamus, potentially “tricking” it into thinking that energy or food intake is sufficient so there is no need to increase appetite (15,16).
This key ingredient in Recreate has been used for centuries in Ayurvedic Medicine to reduce appetite & food cravings.
Microtea Debilis Extract- Cirsimarin
This naturally occurring compound has demonstrated some impressive properties.
Specifically, it has been shown to be 20 times more potent at stimulating lipolysis in vitro, using fat cells of an animal model, as compared to caffeine (17).
Caffeine is clearly a considerably active compound itself, so for this compound to have such potent effects is nothing short of amazing.
It has also been shown to possess potent anti-lipogenic effects and to decrease adipose tissue deposition in an animal model (18).
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.